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Science & Publications


Explore our latest peer-reviewed research and contributions to the scientific community.

Wobble tRNA modification and hydrophilic amino acid patterns dictate protein fate.

Nat Commun (2021)

Codon-specific translation reprogramming promotes resistance to targeted therapy.

Nature (2018)

Elp3 links tRNA modification to IRES-dependent translation of LEF1 to sustain metastasis in breast cancer.

J Exp Med (2016)

Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine.

J Exp Med (2015)

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THERAtRAME

Eradicating cancer with tRNA modulators

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